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Exhibition Review | Microscopy's new era of force display intelligent technology ultra-high resolution microscopy system unveiled at CSSCR2021

2021年12月12-15日,“中国干细胞第十一届年会”在广州圆满召开,众多干细胞领域专家齐聚一堂,以学术交流为核心,旨在推动中国干细胞与再生医学领域的发展,促进干细胞研究人员深入交流合作,共同探讨干细胞研究领域的关键科学问题。

On December 12-15, 2021, the "11th Annual Conference of Chinese Stem Cells" was successfully held in Guangzhou, where many experts in the field of stem cells gathered together to promote the development of stem cells and regenerative medicine in China, promote in-depth exchanges and cooperation among stem cell researchers, and jointly discuss key scientific issues in the field of stem cell research.

iSTORM| Beyond the limits of optics is not a dream

Based on the 2014 Nobel Prize in Chemistry, Lixian Intelligent Technology independently developed the iSTORM super-resolution microscopic system, which "broke" the optical diffraction limit by applying a series of physical principles, chemical mechanisms and algorithms, and increased the resolution of the optical microscope by ten times, enabling human beings to observe the biological microscopic world from an unprecedented perspective below 200nm.

Advanced technology, 20nm ultra-high resolution, 3D imaging

Using STORM stochastic optical reconstruction technology, adding cylindrical mirror design, the resolution in the XY axis is 20nm, the Z axis resolution is up to 50nm, and it has 3D imaging functions.

Multi-channel simultaneous imaging optical path design, high stability

Proprietary multi-channel simultaneous imaging optical path design provides a stable optical path. The self-developed imaging spectroscopic optical path can ensure that the optical path between channels is relatively independent, so that the fluorescence emitted by the sample can be received by the detector with maximum efficiency, and the crosstalk between channels can be minimized. In combination with the optimal dye protocol and the best imaging buffer formulation, multi-channel simultaneous imaging enables ultra-high-resolution imaging of 20 nm in a time range of seconds to ten minutes.

Physical sample locking design, locking accuracy 1nm

Using nano-level real-time dynamic locking technology, the sample drift is corrected by real-time physical compensation, no preheating, ready to use, easy to operate, free from the influence of the environment such as airflow, temperature change, noise, mechanical vibration, etc. on the sample position, in the high floor, noisy, vibration, normal temperature environment can also be stable imaging, so it has the characteristics of high efficiency, simplicity, good adaptability to the environment, friendly and easy to use.

"Point-and-shoot" operation, easy to learn and use

The software integrates a variety of imaging algorithms, and presents ultra-high-resolution image reconstruction results and detailed parameters in real time when collecting data, "what you see is what you need", the operation is streamlined, and it is simple and easy to use. It has five characteristics: simple and easy to use shooting process, real-time transparency of parameter optimization, real-time reconstruction of super-resolution images, automatic user data management, and post-analysis of image data. In addition, the optimized sample preparation protocol is easier for experimenters to grasp and practice. Even new to technology can control the system and achieve ideal super-resolution imaging results in less than 2 hours after a simple technical explanation.

Miniview MN-100 | intelligent cell monitoring assistant in the incubator

miniview MN-100 is a mini scientific research instrument for real-time detection of cell growth status, which can be placed in multiple incubators to observe cell growth status in an intuitive and real-time way on the PC side, providing video backtracking, confluence analysis, growth curve and other analysis functions, which is perfectly suitable for most cell growth research, providing a one-stop solution for cell quality control and monitoring, and seamlessly connecting the subsequent experimental process.

Uninterrupted monitoring to never miss a moment of your cell culture

24/7 uninterrupted quantitative display of cell culture status, real-time fitting of cell growth curves, providing video backtracking function, and effectively avoiding mycoplasma contamination caused by traditional methods, reducing the risk of experimental failure.

Intelligent analysis, contact line reminder, experiment into the "lazy" era

The image analysis function provides accurate quantitative data on confluency to provide reliable support for experimental results, and can customize the cell growth confluency warning line according to experimental needs, and the contact email reminder function makes the experimental arrangement more accurate.

High compatibility, good economy, no invisible consumables consumption

The use of follow-up fixed focus technology enables free focusing in the z-axis, which is compatible with most conventional incubators on the market and requires no special consumables.

One machine multi-functional, multi-scenario applicable, experimental "small" helper

Support the application of multiple experimental scenarios including tumor cell function monitoring, in vitro drug function screening, pharmacokinetics, targeted drug screening, etc.

The 11th China Stem Cell Annual Conference (CSSCR2021) has been successfully concluded, but Ningbo Lixian will not stop the pace of scientific and technological innovation. Starting from the scientific research market, it gradually expanded to the clinical pathological diagnosis and testing, drug discovery and quality control, and industrial optical detection and measurement markets. While building an interdisciplinary technology platform and accumulating technology, it holds high the banner of the first ultra-high resolution microscopy company with independent intellectual property rights in China, and establishes a brand image with both R&D and product transformation technology strength. It is believed that the rise of domestic ultra-high-resolution microscopy technology is unstoppable.

About Us:

Ningbo Lixian Intelligent Technology Co., Ltd. (INVIEW) is a scientific and technological enterprise specializing in ultra-high resolution microscopy technology and product research and development, relying on the automatic control, new generation information technology of Fudan University and the biology, optics, image processing and other technologies of the Hong Kong University of Science and Technology, with optics, biology, automatic control, machinery, information technology and other interdisciplinary technical teams, the 2014 Nobel Prize in Chemistry technology industrialization, launched the ultra-high resolution microscopy imaging system iSTORM, A series of products such as Cellaview, the intelligent monitoring assistant of cells, help people observe the microscopic world from an unprecedented perspective, break through the limit, and see things like never before.

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